In Neverwinter, the game changes when you hit level 70 (the current level cap). Things transition from questing to Campaigns and End of Game content. Since there have been several expansions, things kind of explode when you hit 70, and tons of new quests to start campaigns pop up.
It's very difficult to know what to do first, and can be a bit intimidating. Also, the different campaigns have different difficulty settings, that are not readily apparent. If your overall geat score is too low, you'll get spanked. Over and over. Everywhere you go. It's not fun. Trust me. ;)
Here's a great guide I found that tells you what order to do the campaigns in. It's helping me a LOT right now. :)